Which Instrument to Use?

Each NMR spectrometer in the PMRC Core facility is tailored to support specific applications with their equipment configurations and time allocation rules optimized accordingly. These are our recommendations for different types of sample analysis that our users can carry out with a range of spectrometers:

Solution-State NMR

For samples that are available at > 5 mg:

1D 1H NMR: AVQ-400 , JEOL-400, NEO-500, and NEO-501.

2D NMR: NEO-500, NEO-501, AV-600, and AV-700

13C NMR: NEO-500, NEO-501, and AV-600. You can also the AVQ-400 or JEOL-400 if sample is available at > 10 mg.

19F NMR:  AVQ-400, JEOL-400, NEO-500, NEO-501, and AV-600

31P NMR  AVQ-400, JEOL-400, NEO-500, NEO-501, and AV-600

For samples that are available at < 5 mg

1D 1H NMR: JEOL-400, NEO-500, NEO-501, AV-600, and AV-700

2D NMR: NEO-501, AV-600, and AV-700

13C NMR: NEO-501, AV-600

19F NMR: JEOL-400, NEO-500, NEO-501, and AV-600

31P NMR:NEO-500, NEO-501, and AV-600

Here is the sensitivity comparison for our three high-field instruments for further guidance:

Sensitivity for Nucleus (a.u.)

JEOL-400

NEO-500

NEO-501

AV-600

AV-700

1H

670

960

1770

1560

5500

13C{1H}

275

360

850

1115

220

19F (19F{1H})

(700)

475 (830)

1650

1705

N/A

31P{1H}

115

460

560

740

N/A

Solid-State and Diffusion NMR or Micro-imaging

Please consult with CoC-NMR staff before planning for such experiments by contacting them at nmr_lab@lists.berkeley.edu.